The pick six begins in Friday's fifth race with two carryovers - $119,741 in the main pool and $170,623 in the single ticket jackpot pool.
The pool of new money is likely to surpass $600,000.
The bet begins with a $50,000 claimer at 5 1-2 furlongs for maidens. In a field of 10, Time for Cioppino (2) and Luke's On Fire (8) will be prominent on many tickets.